α-Chlorination of Long-chain Aliphatic Acids

Long-chain aliphatic fatty acids and phytanic acid simultaneously measured by dual-column capillary chromatography.

A method is described for simultaneously measuring long-chain aliphatic fatty acids and phytanic acid in plasma, for the diagnosis of disorders associated with peroxisomal defects, eliminating the need for two separate chromatographic runs to resolve all of the analytes. In addition, the simultaneous, dual-column analysis allows confirmation of the identity and quantity of the individual fatty ...

Aliphatic medium chain tricarboxylic acids in rat urine.

Three aliphatic tricarboxylic acids have been found in rat urine. They have been identified as 6-carboxy-5-undecenedioic acid, 6-carboxy-5-dodecenedoic acid, and 6-carboxy-5-tridecenedioic acid. The carbon skeleton structure was determined by mass spectra of the hydrogenated methyl esters. The double bond position was determined after osmium tetroxide oxidation followed by trifluoroacetylation ...

Inhibition of Thermophilic Anaerobic Digestion of Waste Food by Long Chain Fatty Acids and Propionate

Antibacterial action and chemical constitution in long-chain aliphatic bases.

The success of sulphanilamide as a chemotherapeutic agent encourages the investigation of other classes of compound for antibacterial properties. The compounds 'described in this paper were the long-chain amines, amidines and guanidines which had been shown by King, Lourie & Yorke [1938] to possess remarkable trypanocidal powers. They were chosen because they had a proved biological action, and...

Aliphatic long-chain C20 polyesters from olefin metathesis.

Self-metathesis of undecenoic acid with [(PCy3)2Cl2Ru=CHPh] (2), followed by exhaustive hydrogenation yielded pure 1,20-eicosanedioic acid (5) (>99%) free of side-products from isomerization. Polycondensation with eicosane-1,20-diol (6), formed by reduction of the diol, yielded polyester 20,20 (Tm = 108 °C). By comparison, the known ADMET polymerization of undec-10-enyl undec-10-enoate (7), and...